diff --git a/goldens/public-api/angular_devkit/build_angular/index.md b/goldens/public-api/angular_devkit/build_angular/index.md
index e7a6a890e1a1..5a7c1a144a75 100644
--- a/goldens/public-api/angular_devkit/build_angular/index.md
+++ b/goldens/public-api/angular_devkit/build_angular/index.md
@@ -178,7 +178,7 @@ export interface KarmaBuilderOptions {
     include?: string[];
     inlineStyleLanguage?: InlineStyleLanguage_2;
     karmaConfig: string;
-    main: string;
+    main?: string;
     poll?: number;
     polyfills?: Polyfills_2;
     preserveSymlinks?: boolean;
diff --git a/packages/angular_devkit/build_angular/src/builders/karma/index.ts b/packages/angular_devkit/build_angular/src/builders/karma/index.ts
index d8ca058507d8..f406fa769047 100644
--- a/packages/angular_devkit/build_angular/src/builders/karma/index.ts
+++ b/packages/angular_devkit/build_angular/src/builders/karma/index.ts
@@ -111,6 +111,17 @@ export function execute(
         throw new Error('The builder requires a target.');
       }
 
+      if (!options.main) {
+        webpackConfig.entry ??= {};
+        if (typeof webpackConfig.entry === 'object' && !Array.isArray(webpackConfig.entry)) {
+          if (Array.isArray(webpackConfig.entry['main'])) {
+            webpackConfig.entry['main'].push(getBuiltInMainFile());
+          } else {
+            webpackConfig.entry['main'] = [getBuiltInMainFile()];
+          }
+        }
+      }
+
       const projectMetadata = await context.getProjectMetadata(projectName);
       const sourceRoot = (projectMetadata.sourceRoot ?? projectMetadata.root ?? '') as string;
 
@@ -169,3 +180,23 @@ export function execute(
 
 export { KarmaBuilderOptions };
 export default createBuilder<Record<string, string> & KarmaBuilderOptions>(execute);
+
+function getBuiltInMainFile(): string {
+  const content = Buffer.from(
+    `
+  import { getTestBed } from '@angular/core/testing';
+  import {
+    BrowserDynamicTestingModule,
+    platformBrowserDynamicTesting,
+   } from '@angular/platform-browser-dynamic/testing';
+
+  // Initialize the Angular testing environment.
+  getTestBed().initTestEnvironment(BrowserDynamicTestingModule, platformBrowserDynamicTesting(), {
+    errorOnUnknownElements: true,
+    errorOnUnknownProperties: true
+  });
+`,
+  ).toString('base64');
+
+  return `ng-virtual-main.js!=!data:text/javascript;base64,${content}`;
+}
diff --git a/packages/angular_devkit/build_angular/src/builders/karma/schema.json b/packages/angular_devkit/build_angular/src/builders/karma/schema.json
index 35a9de5054ee..1d55ee6434c9 100644
--- a/packages/angular_devkit/build_angular/src/builders/karma/schema.json
+++ b/packages/angular_devkit/build_angular/src/builders/karma/schema.json
@@ -255,7 +255,7 @@
     }
   },
   "additionalProperties": false,
-  "required": ["main", "tsConfig", "karmaConfig"],
+  "required": ["tsConfig", "karmaConfig"],
   "definitions": {
     "assetPattern": {
       "oneOf": [
diff --git a/packages/angular_devkit/build_angular/src/builders/karma/tests/setup.ts b/packages/angular_devkit/build_angular/src/builders/karma/tests/setup.ts
index 03693ac3e9b3..49d0633f7a21 100644
--- a/packages/angular_devkit/build_angular/src/builders/karma/tests/setup.ts
+++ b/packages/angular_devkit/build_angular/src/builders/karma/tests/setup.ts
@@ -20,8 +20,7 @@ export const KARMA_BUILDER_INFO = Object.freeze({
  * Also disables progress reporting to minimize logging output.
  */
 export const BASE_OPTIONS = Object.freeze<Schema>({
-  main: 'src/test.ts',
-  polyfills: 'src/polyfills.ts',
+  polyfills: ['zone.js', 'zone.js/testing', '@angular/localize/init'],
   tsConfig: 'src/tsconfig.spec.json',
   karmaConfig: 'karma.conf.js',
   browsers: 'ChromeHeadlessCI',
diff --git a/packages/angular_devkit/build_angular/src/webpack/configs/common.ts b/packages/angular_devkit/build_angular/src/webpack/configs/common.ts
index 98f5dd550c50..2b585b8e71e5 100644
--- a/packages/angular_devkit/build_angular/src/webpack/configs/common.ts
+++ b/packages/angular_devkit/build_angular/src/webpack/configs/common.ts
@@ -130,7 +130,7 @@ export async function getCommonConfig(wco: WebpackConfigOptions): Promise<Config
       if (Array.isArray(entryPoints['main'])) {
         entryPoints['main'].unshift(zoneTestingEntryPoint);
       } else {
-        entryPoints['main'] = [zoneTestingEntryPoint, entryPoints['main'] as string];
+        entryPoints['main'] = [zoneTestingEntryPoint];
       }
     }
   }
diff --git a/packages/angular_devkit/build_angular/test/hello-world-app/angular.json b/packages/angular_devkit/build_angular/test/hello-world-app/angular.json
index 0200444814cc..87edec62bceb 100644
--- a/packages/angular_devkit/build_angular/test/hello-world-app/angular.json
+++ b/packages/angular_devkit/build_angular/test/hello-world-app/angular.json
@@ -117,8 +117,8 @@
         "test": {
           "builder": "@angular-devkit/build-angular:karma",
           "options": {
-            "main": "src/test.ts",
-            "polyfills": "src/polyfills.ts",
+            "polyfills": ["zone.js", "zone.js/testing", "@angular/localize/init"],
+
             "tsConfig": "src/tsconfig.spec.json",
             "karmaConfig": "karma.conf.js",
             "browsers": "ChromeHeadlessCI",
diff --git a/packages/angular_devkit/build_angular/test/hello-world-app/src/test.ts b/packages/angular_devkit/build_angular/test/hello-world-app/src/test.ts
deleted file mode 100644
index a1358960f3e7..000000000000
--- a/packages/angular_devkit/build_angular/test/hello-world-app/src/test.ts
+++ /dev/null
@@ -1,22 +0,0 @@
-/**
- * @license
- * Copyright Google LLC All Rights Reserved.
- *
- * Use of this source code is governed by an MIT-style license that can be
- * found in the LICENSE file at https://angular.io/license
- */
-
-// This file is required by karma.conf.js and loads recursively all the .spec and framework files
-
-import 'zone.js/testing';
-import { getTestBed } from '@angular/core/testing';
-import {
-  BrowserDynamicTestingModule,
-  platformBrowserDynamicTesting,
-} from '@angular/platform-browser-dynamic/testing';
-
-// First, initialize the Angular testing environment.
-getTestBed().initTestEnvironment(BrowserDynamicTestingModule, platformBrowserDynamicTesting(), {
-  errorOnUnknownElements: true,
-  errorOnUnknownProperties: true
-});
diff --git a/packages/angular_devkit/build_angular/test/hello-world-app/src/tsconfig.spec.json b/packages/angular_devkit/build_angular/test/hello-world-app/src/tsconfig.spec.json
index dba226c49414..7ece4f757a0d 100644
--- a/packages/angular_devkit/build_angular/test/hello-world-app/src/tsconfig.spec.json
+++ b/packages/angular_devkit/build_angular/test/hello-world-app/src/tsconfig.spec.json
@@ -7,7 +7,6 @@
     ]
   },
   "files": [
-    "test.ts",
     "polyfills.ts"
   ],
   "include": [
diff --git a/packages/angular_devkit/build_angular/test/hello-world-lib/projects/lib/src/test.ts b/packages/angular_devkit/build_angular/test/hello-world-lib/projects/lib/src/test.ts
deleted file mode 100644
index 88ee02586b8d..000000000000
--- a/packages/angular_devkit/build_angular/test/hello-world-lib/projects/lib/src/test.ts
+++ /dev/null
@@ -1,23 +0,0 @@
-/**
- * @license
- * Copyright Google LLC All Rights Reserved.
- *
- * Use of this source code is governed by an MIT-style license that can be
- * found in the LICENSE file at https://angular.io/license
- */
-
-// This file is required by karma.conf.js and loads recursively all the .spec and framework files
-
-import 'zone.js';
-import 'zone.js/testing';
-import { getTestBed } from '@angular/core/testing';
-import {
-  BrowserDynamicTestingModule,
-  platformBrowserDynamicTesting
-} from '@angular/platform-browser-dynamic/testing';
-
-// First, initialize the Angular testing environment.
-getTestBed().initTestEnvironment(BrowserDynamicTestingModule, platformBrowserDynamicTesting(), {
-  errorOnUnknownElements: true,
-  errorOnUnknownProperties: true
-});
diff --git a/packages/angular_devkit/build_angular/test/hello-world-lib/projects/lib/tsconfig.lib.json b/packages/angular_devkit/build_angular/test/hello-world-lib/projects/lib/tsconfig.lib.json
index 953df1b95597..fe12470400e2 100644
--- a/packages/angular_devkit/build_angular/test/hello-world-lib/projects/lib/tsconfig.lib.json
+++ b/packages/angular_devkit/build_angular/test/hello-world-lib/projects/lib/tsconfig.lib.json
@@ -7,7 +7,6 @@
     "types": []
   },
   "exclude": [
-    "src/test.ts",
     "**/*.spec.ts"
   ]
 }
diff --git a/packages/angular_devkit/build_angular/test/hello-world-lib/projects/lib/tsconfig.spec.json b/packages/angular_devkit/build_angular/test/hello-world-lib/projects/lib/tsconfig.spec.json
index f1c08bf277d3..eae9b9ae9c29 100644
--- a/packages/angular_devkit/build_angular/test/hello-world-lib/projects/lib/tsconfig.spec.json
+++ b/packages/angular_devkit/build_angular/test/hello-world-lib/projects/lib/tsconfig.spec.json
@@ -6,9 +6,6 @@
       "jasmine"
     ]
   },
-  "files": [
-    "src/test.ts"
-  ],
   "include": [
     "**/*.spec.ts",
     "**/*.d.ts"
diff --git a/packages/schematics/angular/application/files/src/test.ts.template b/packages/schematics/angular/application/files/src/test.ts.template
deleted file mode 100644
index 0e689016906e..000000000000
--- a/packages/schematics/angular/application/files/src/test.ts.template
+++ /dev/null
@@ -1,12 +0,0 @@
-// This file is required by karma.conf.js and loads recursively all the .spec and framework files
-import { getTestBed } from '@angular/core/testing';
-import {
-  BrowserDynamicTestingModule,
-  platformBrowserDynamicTesting
-} from '@angular/platform-browser-dynamic/testing';
-
-// First, initialize the Angular testing environment.
-getTestBed().initTestEnvironment(BrowserDynamicTestingModule, platformBrowserDynamicTesting(), {
-  errorOnUnknownElements: true,
-  errorOnUnknownProperties: true
-});
diff --git a/packages/schematics/angular/application/files/tsconfig.spec.json.template b/packages/schematics/angular/application/files/tsconfig.spec.json.template
index c9c241170103..7d40e67dd989 100644
--- a/packages/schematics/angular/application/files/tsconfig.spec.json.template
+++ b/packages/schematics/angular/application/files/tsconfig.spec.json.template
@@ -7,9 +7,6 @@
       "jasmine"
     ]
   },
-  "files": [
-    "src/test.ts"
-  ],
   "include": [
     "src/**/*.spec.ts",
     "src/**/*.d.ts"
diff --git a/packages/schematics/angular/application/index.ts b/packages/schematics/angular/application/index.ts
index e804269d4545..48ed9bb63239 100644
--- a/packages/schematics/angular/application/index.ts
+++ b/packages/schematics/angular/application/index.ts
@@ -210,7 +210,6 @@ function addAppToWorkspaceFile(
         : {
             builder: Builders.Karma,
             options: {
-              main: `${sourceRoot}/test.ts`,
               polyfills: ['zone.js', 'zone.js/testing'],
               tsConfig: `${projectRoot}tsconfig.spec.json`,
               karmaConfig: `${projectRoot}karma.conf.js`,
@@ -231,7 +230,7 @@ function addAppToWorkspaceFile(
   });
 }
 function minimalPathFilter(path: string): boolean {
-  const toRemoveList = /(test.ts|tsconfig.spec.json|karma.conf.js).template$/;
+  const toRemoveList = /(tsconfig.spec.json|karma.conf.js).template$/;
 
   return !toRemoveList.test(path);
 }
diff --git a/packages/schematics/angular/application/index_spec.ts b/packages/schematics/angular/application/index_spec.ts
index 7055f485e7ca..cbc5764331cd 100644
--- a/packages/schematics/angular/application/index_spec.ts
+++ b/packages/schematics/angular/application/index_spec.ts
@@ -61,7 +61,6 @@ describe('Application Schematic', () => {
         '/projects/foo/src/index.html',
         '/projects/foo/src/main.ts',
         '/projects/foo/src/styles.css',
-        '/projects/foo/src/test.ts',
         '/projects/foo/src/app/app.module.ts',
         '/projects/foo/src/app/app.component.css',
         '/projects/foo/src/app/app.component.html',
@@ -164,8 +163,7 @@ describe('Application Schematic', () => {
     const tree = await schematicRunner
       .runSchematicAsync('application', defaultOptions, workspaceTree)
       .toPromise();
-    const { files, extends: _extends } = readJsonFile(tree, '/projects/foo/tsconfig.spec.json');
-    expect(files).toEqual(['src/test.ts']);
+    const { extends: _extends } = readJsonFile(tree, '/projects/foo/tsconfig.spec.json');
     expect(_extends).toBe('../../tsconfig.json');
   });
 
@@ -255,7 +253,6 @@ describe('Application Schematic', () => {
     [
       '/projects/foo/tsconfig.spec.json',
       '/projects/foo/karma.conf.js',
-      '/projects/foo/src/test.ts',
       '/projects/foo/src/app/app.component.css',
       '/projects/foo/src/app/app.component.html',
       '/projects/foo/src/app/app.component.spec.ts',
@@ -285,7 +282,6 @@ describe('Application Schematic', () => {
     [
       '/projects/foo/tsconfig.spec.json',
       '/projects/foo/karma.conf.js',
-      '/projects/foo/src/test.ts',
       '/projects/foo/src/app/app.component.html',
       '/projects/foo/src/app/app.component.spec.ts',
     ].forEach((x) => expect(files).not.toContain(x));
@@ -315,7 +311,6 @@ describe('Application Schematic', () => {
     [
       '/projects/foo/tsconfig.spec.json',
       '/projects/foo/karma.conf.js',
-      '/projects/foo/src/test.ts',
       '/projects/foo/src/app/app.component.css',
       '/projects/foo/src/app/app.component.spec.ts',
     ].forEach((x) => expect(files).not.toContain(x));
@@ -410,7 +405,6 @@ describe('Application Schematic', () => {
           '/src/index.html',
           '/src/main.ts',
           '/src/styles.css',
-          '/src/test.ts',
           '/src/app/app.module.ts',
           '/src/app/app.component.css',
           '/src/app/app.component.html',
@@ -436,7 +430,6 @@ describe('Application Schematic', () => {
       expect(buildOpt.tsConfig).toEqual('tsconfig.app.json');
 
       const testOpt = prj.architect.test.options;
-      expect(testOpt.main).toEqual('src/test.ts');
       expect(testOpt.tsConfig).toEqual('tsconfig.spec.json');
       expect(testOpt.karmaConfig).toEqual('karma.conf.js');
       expect(testOpt.styles).toEqual(['src/styles.css']);
@@ -510,13 +503,13 @@ describe('Application Schematic', () => {
       expect(appTsConfig.extends).toEqual('./tsconfig.json');
       const specTsConfig = readJsonFile(tree, '/tsconfig.spec.json');
       expect(specTsConfig.extends).toEqual('./tsconfig.json');
-      expect(specTsConfig.files).toEqual(['src/test.ts']);
     });
 
     it(`should create correct paths when 'newProjectRoot' is blank`, async () => {
       const workspaceTree = await schematicRunner
         .runSchematicAsync('workspace', { ...workspaceOptions, newProjectRoot: '' })
         .toPromise();
+
       const options = { ...defaultOptions, projectRoot: undefined };
       const tree = await schematicRunner
         .runSchematicAsync('application', options, workspaceTree)
diff --git a/packages/schematics/angular/library/files/src/test.ts.template b/packages/schematics/angular/library/files/src/test.ts.template
deleted file mode 100644
index 0e689016906e..000000000000
--- a/packages/schematics/angular/library/files/src/test.ts.template
+++ /dev/null
@@ -1,12 +0,0 @@
-// This file is required by karma.conf.js and loads recursively all the .spec and framework files
-import { getTestBed } from '@angular/core/testing';
-import {
-  BrowserDynamicTestingModule,
-  platformBrowserDynamicTesting
-} from '@angular/platform-browser-dynamic/testing';
-
-// First, initialize the Angular testing environment.
-getTestBed().initTestEnvironment(BrowserDynamicTestingModule, platformBrowserDynamicTesting(), {
-  errorOnUnknownElements: true,
-  errorOnUnknownProperties: true
-});
diff --git a/packages/schematics/angular/library/files/tsconfig.lib.json.template b/packages/schematics/angular/library/files/tsconfig.lib.json.template
index 353a24b4ac75..d8d4b0b23347 100644
--- a/packages/schematics/angular/library/files/tsconfig.lib.json.template
+++ b/packages/schematics/angular/library/files/tsconfig.lib.json.template
@@ -9,7 +9,6 @@
     "types": []
   },
   "exclude": [
-    "src/test.ts",
     "**/*.spec.ts"
   ]
 }
diff --git a/packages/schematics/angular/library/files/tsconfig.spec.json.template b/packages/schematics/angular/library/files/tsconfig.spec.json.template
index 2108b9b916f1..2490345bafff 100644
--- a/packages/schematics/angular/library/files/tsconfig.spec.json.template
+++ b/packages/schematics/angular/library/files/tsconfig.spec.json.template
@@ -7,9 +7,6 @@
       "jasmine"
     ]
   },
-  "files": [
-    "src/test.ts"
-  ],
   "include": [
     "**/*.spec.ts",
     "**/*.d.ts"
diff --git a/packages/schematics/angular/library/index.ts b/packages/schematics/angular/library/index.ts
index 69524593bcc2..70e77f788836 100644
--- a/packages/schematics/angular/library/index.ts
+++ b/packages/schematics/angular/library/index.ts
@@ -108,7 +108,6 @@ function addLibToWorkspaceFile(
         test: {
           builder: Builders.Karma,
           options: {
-            main: `${projectRoot}/src/test.ts`,
             tsConfig: `${projectRoot}/tsconfig.spec.json`,
             polyfills: ['zone.js', 'zone.js/testing'],
             karmaConfig: `${projectRoot}/karma.conf.js`,
diff --git a/packages/schematics/angular/library/index_spec.ts b/packages/schematics/angular/library/index_spec.ts
index 3b775211a904..e2ec7a47b2a5 100644
--- a/packages/schematics/angular/library/index_spec.ts
+++ b/packages/schematics/angular/library/index_spec.ts
@@ -57,7 +57,6 @@ describe('Library Schematic', () => {
         '/projects/foo/README.md',
         '/projects/foo/tsconfig.lib.json',
         '/projects/foo/tsconfig.lib.prod.json',
-        '/projects/foo/src/test.ts',
         '/projects/foo/src/my-index.ts',
         '/projects/foo/src/lib/foo.module.ts',
         '/projects/foo/src/lib/foo.component.spec.ts',